VP, Commercial Excellence, Upper Columbia Region (Golden)

Overview Sequel, headquartered in Manchester, New Hampshire, is a company developing the next generation of transformative drug‑delivery advancements starting with diabetes. Sequel’s approach is to look at diabetes management holistically to advance systems that make living with diabetes simpler and easier for all. Sequel’s flagship product, the twiist Automated Insulin Delivery (AID) System, launched in July 2025 forpeople with type 1 diabetes providing them with personalized diabetes management.

Role Summary Sequel Med Tech is seeking a highly strategic and analytically driven Vice President, Commercial Excellence to lead and evolve our commercial operations function. This leader will serve as the head of Sales Operations while acting as a critical thought partner to the SVP of Market Access, Sales and Government Affairs.

The VP, Commercial Excellence will be responsible for building and optimizing the infrastructure that supports commercial execution, and synthesizing insights across Sales, Market Access, Trade, and Government Affairs to inform enterprise‑level decision‑making. This incumbent will translate complex, cross‑functional dynamics into clear, data‑driven narratives that shape commercial strategy, guide investment decisions, and inform the executive team and Board.

As a growth‑stage company this is a highly hands‑on, “working VP” role. The ideal candidate will be equally comfortable setting strategy and executing it—rolling up their sleeves to build, analyse, and problem‑solve directly. The role requires a builder’s mindset: someone who thrives in ambiguity, enjoys creating scalable processes from the ground up, and takes pride in designing solutions that will evolve with the company’s growth.

Responsibilities

Lead and evolve Sequel’s commercial operations function to support growth and long‑term scalability.

Serve as a strategic advisor to the SVP, providing a holistic view of commercial performance and forward‑looking opportunities.

Build a best‑in‑class Commercial Excellence function that integrates analytics, planning, and operational execution.

Balance strategic leadership with hands‑on execution, actively contributing to analyses, building models and solving complex business problems directly.

Develop and lead a high‑performing team across sales operations, analytics and commercial planning.

Own the development of a comprehensive commercial analytics framework that integrates data across sales, market access, trade and government affairs.

Identify key business drivers and interdependencies, translating them into actionable insights and strategic recommendations.

Lead scenario modeling and predictive analytics to forecast performance under varying market conditions.

Personally engage in deep‑dive analyses and model building.

Develop and refine KPIs and dashboards that provide visibility into performance and leading indicators of future growth.

Synthesize complex datasets and cross‑functional inputs into clear, compelling narratives for executive leadership and the Board.

Translate developments (e.g. changes in payor coverage, channel expansion, policy shifts) into quantified commercial impact.

Lead commercial forecasting and long‑range planning processes, including revenue projections and market expansion scenarios.

Partner with Finance and executive leadership on annual planning, investment prioritisation and resource allocation.

Oversee all core sales operations capabilities, including sales forecasting and planning, territory design and alignment, incentive compensation strategy and administration, and CRM and commercial systems optimisation.

Ensure operational excellence in execution while continuously improving systems and processes.

Directly contribute to building and refining tools, processes and outputs.

Partner closely with Sales leadership to optimise field effectiveness and productivity.

Partner with Market Access, Trade and Government Affairs to understand evolving dynamics in coverage, reimbursement and channel strategy.

Integrate insights from these functions into commercial forecasts and strategic plans.

Ensure alignment between commercial strategy and execution across all channels and stakeholders.

Play a leadership role in ongoing launch optimisation, using real‑time data to refine strategy and execution.

Identify opportunities to accelerate growth, expand market penetration and improve commercial return on investment.

Monitor competitive dynamics and market trends to inform strategic adjustments.

Build organisational capabilities that scale with company growth.

Act as a senior leader within the commercial organisation, contributing to broader company strategy.

Minimum Requirements

Education: Bachelor’s degree in Business, Life Sciences or related field; MBA or advanced degree preferred.

Experience: 12–15+ years of progressive experience in commercial operations, sales operations, commercial analytics or related roles within medical device, pharmaceutical or healthcare industries.

Experience supporting or leading U.S. product launches in regulated environments.

Candidates must reside in the United States.

Required Knowledge, Skills and Abilities

Exceptional analytical and strategic thinking skills, with the ability to connect disparate data points into a cohesive business narrative.

Demonstrated experience in forecasting, scenario modelling and data‑driven strategic planning.

Deep expertise in sales operations, including territory design, incentive compensation and CRM systems.

Some familiarity with market access, including payor dynamics and reimbursement models.

Experience with international commercial operations or global market dynamics preferred.

Prior experience in high‑growth or startup environments preferred.

Exposure to market access, reimbursement and trade strategy preferred.

Proven ability to influence senior leadership and communicate effectively with executive teams and Boards.

Track record of building and leading high‑performing teams.

Demonstrated willingness and ability to operate as a player‑coach; leading while also executing at a high level.

Strong cross‑functional leadership skills with the ability to operate effectively in a complex, matrixed environment.

High level of business judgment, intellectual curiosity and ownership.

Ability to travel frequently to support field engagement, cross‑functional alignment and executive collaboration.

Ability to regularly work from Sequel’s Manchester, NH or Marlborough, MA office preferred but not required.

Equal Employment Opportunity Statement Sequel Med Tech provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, colour, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

Benefits At Sequel, we believe that when you thrive, we thrive. That’s why our benefits package is designed to support you from day one. You’ll be automatically enrolled in our 401k plan, featuring a 6% company match and 100% immediate vesting.

We’re committed to your well‑being and understand the unique needs of employees and families living with diabetes, so we offer capped out‑of‑pocket insulin costs and GLP‑1 coverage across all plans. You’ll have access to a variety of Meritain health insurance plans to suit your needs and can also take advantage of Flexible Spending Accounts (FSAs) or Health Savings Account (HSA). Our comprehensive benefits package includes vision and dental coverage, plus voluntary options such as long‑term disability, accident, critical illness, hospital indemnity, and even discounts for pet care.In addition, we provide employer‑paid short‑term disability and life insurance for extra peace of mind.

We know the importance of taking time to rest and recharge. That’s why Sequel offers flexible PTO, generous paid holidays and flex time options to help you balance work and life when you need it most. Our team enjoys a culture built on hard work, fun and genuine support. At Sequel, you’re not just starting a job, you’re building a rewarding career and a brighter future. Join us and let’s thrive together!

Environmental, Safety and Physical Work Conditions

Ensures environmental consciousness and safe practices are exhibited in decisions.

Use of computer and telephone equipment and other related office accessories/devices to complete assignments.

May work extended hours during peak business cycles.

Physical requirements such as lifting specific weights.

Some travelling is expected.

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